Fig.1

Plasma or serum activity concentrations in percentage injected activity per liter as a function of time in hours post-injection for ⁸⁹Zr-huJ591 (191.3 ± 9 MBq, 25 mg) [10], ⁸⁹Zr-trastuzumab (185 MBq, 50 mg) [11], ⁸⁹Zr-pertuzumab (74 MBq, 20 or 50 mg) [12], ⁸⁹Zr-DFO-MSTP2109A (184 MBq, 10 mg) [13] and ⁸⁹Zr-AlbudAb (14 MBq, 1 mg) [14]. The bold lines represent the input functions used for the simulations, and the dashed lines represent the input functions not included in the simulations. %IA/L = percentage injected activity per liter, h p.i. = hours post-injection