Fig. 5
A 41-year-old female patient was diagnosed with a left frontal meningeal metastasis 20 months after surgical removal of the left lacrimal gland ACC. Pre-therapy 68 Ga-PSMA-617 PET/CT (A–C) demonstrated intense PSMA uptake of tumor (green arrow, SUVmax 7.0). 68 Ga-PSMA-617 PET/CT reexamination at 9 weeks after the 1st cycle of PSMA RLT (D–F) and 8 weeks after the 3rd cycle of PSMA RLT (G–I) revealed significantly decreased tracer uptake of tumor (red arrow, SUVmax 3.5; blue arrow, SUVmax 1.1), which reached the level of CR according to modified PERSIST criteria. However, 18F-FDG PET/CT (J–L) always exhibited no positive lesions (orange arrow)