Table 2 Multivariate analyses of factors related to radioiodine refractory differentiated thyroid cancer
Variable | Odds ratio | 95% CI | P-value |
|---|---|---|---|
Age (≥ 48/ < 48 years) | 1.037 | 1.007–1.069 | 0.015* |
Operation frequency (once/twice or more) | 0.284 | 0.079–1.016 | 0.053 |
Autoimmune thyroid disease (yes/no) | 0.631 | 0.308–1.294 | 0.209 |
Tumor diameter (≥ 18.5/ < 18.5 mm) | 1.002 | 0.788–1.274 | 0.988 |
Clinical stage (I/II/III/IVA/IVB) | 0.803 | 0.340–1.894 | 0.616 |
Recurrence between the operation and iodine-131 treatment (yes/no) | 7.362 | 2.388–22.698 | 0.001* |
Time from the first operation to the first iodine-131 treatment (≥ 16/ < 16 months) | 1.005 | 0.996–1.014 | 0.290 |
Site of metastasis (single-site/multi-partial metastases) | 4.365 | 1.593–11.965 | 0.004* |
Uptake of 18F-FDG (negative/positive) | 39.534 | 18.590–84.076 | 0.001* |