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EJNMMI Research
Fig. 3 | EJNMMI Research

Fig. 3

From: Toward in vivo proof of binding of 18F-labeled inhibitor [18F]TRACK to peripheral tropomyosin receptor kinases

Fig. 3

Uptake into KM12 tumor and muscle tissue. A Representative PET images as maximum intensity projections (MIP) after 5 min (left), 60 min (middle) and 120 min (right) post-injection of 5–7 MBq [18F]TRACK into a KM12 tumor-bearing athymic nude mouse. B Time–activity curves (TACs) for KM12 tumor and muscle tissue over 60 min after injection of [18F]TRACK. C Calculated tumor-to-muscle ratio over time from the KM12 tumor and muscle tissue data in B. D TACs for KM12 tumor and muscle tissue over 120 min after injection of [18F]TRACK. C–D All graphical data are shown as mean ± SEM from n experiments. B and C show data from n = 6 experiments; D only shows data from n = 2 experiments

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