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EJNMMI Research
Fig. 3 | EJNMMI Research

Fig. 3

From: [18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice

Fig. 3

In vivo [18F]ROStrace retention is increased in the APP/PS1 model of AD and demonstrates a female sex bias. Sagittal view of [18F]ROStrace SUVR40-60 PET images collected from both sexes of WT and APP/PS1 mice at 5 mo., 10 mo., and 16 mo. Brain subregions derived from Mirrione mouse brain atlas. Ctx: cortex, OB; olfactory bulb, BFS: basal forebrain septum, Hip: hippocampus, HyTh: hypothalamus, SC: superior colliculi, IC: inferior colliculi, Cb: cerebellum, BS: brain stem, Th: thalamus, PAG: periaqueductal gray, and Mb: midbrain

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