Fig. 2
Regional differences in [18F]ROStrace uptake from 9 VOIs presented as standard uptake value ratios from 40–60 min post-injection (SUVR40-60) in WT and APP/PS1 mice at a 5 mo. old: APP/PS1 group: n = 6 for female, and n = 9 for male; WT group: n = 9 per gender, b 10 mo. old: APP/PS1 group: n = 4 per gender; WT group: n = 6 per gender, and c 16 mo. old: APP/PS1 group: n = 6 for female, and n = 12 for male; WT group: n = 10 per gender. The statistical significance of p value calculated by two-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)