Skip to main content

Table 6 A. Observed frequencies (n) and overall differences (Fisher’s exact test) in incidence of peri-bladder artefacts between the cohorts. Results from post hoc pairwise Z-tests with Bonferroni correction for multiple testing are shown as p values per cohort. B. Concordance of incidence, type, and severity of peri-bladder artefacts. C. Logistic regression analysis assessing the relation between administration of furosemide or choice of tracer on the incidence of peri-bladder artefacts

From: Effects of furosemide and tracer selection on urinary activity and peri-bladder artefacts in PSMA PET/CT: a single-centre retrospective study

A. Observed frequencies (n) and overall differences (Fisher’s exact test) in incidence of peri-bladder artefacts between the cohorts. Results from post hoc pairwise Z-tests with Bonferroni correction for multiple testing are shown as p values per cohort

  

Type, severity

G−

G+

F−

F+

totals

Peri-bladder artefacts

Yes (any)

 

9

1

26

6

42

  

Halo, mild

6

1

8

2

17

  

Halo, severe

1

0

14

0

15

  

Flare, mild

8

1

10

6

25

  

Flare, severe

1

0

14

0

15

 

No

 

42

49

25

44

160

P value

  

1.000

0.001

< 0.001

0.310

 

B. Concordance of incidence, type, and severity of peri-bladder artefacts

Peri-bladder artefacts

 

Halo

  
  

No

Mild

Severe

Flare

No

160

2

0

 

Mild

10

13

2

 

Severe

0

2

13

C. Logistic regression analysis assessing the relation between administration of furosemide or choice of tracer on the incidence of peri-bladder artefacts

 

B

SE

Odds ratio (95% CI)

P value

Variables

    

Radiopharmaceutical

1.887

1.296

6.602 (0.520–83.760)

0.145

Furosemide

− 1.500

1.348

0.223 (0.016–3.130)

0.266

SUVmax bladder

0.074

0.035

1.077 (1.006–1.153)

0.033

Interaction effects

    

SUVmax bladder * radiopharmaceutical

− 0.017

0.019

0.983 (0.947–1.021)

0.378

SUVmax bladder * furosemide

0.038

0.029

1.038 (0.981–1.099)

0.196

  1. Bold values are significant
  2. Italic numbers are subcategories of "Yes (any)"
  3. Overall differences between cohorts p < 0.001
  4. B, b-coefficient; SE, standard error for b-coefficient; CI, confidence interval