Table 1 Post-PET biodistribution results from wild type (WT) and tau knockout (KO) mice (n = 6/group) with % injected dose (ID)/mg of tissue ± standard deviation (SD) after IV injection of [¹¹C]MPC-6827 (3.7 ± 0.05 MBq); **p = 0.004 for brain uptake

From: Preliminary mechanistic insights of a brain-penetrant microtubule imaging PET ligand in a tau-knockout mouse model