Alzheimer’s disease pattern derived from relative cerebral flow as an alternative for the metabolic pattern using SSM/PCA

EJNMMI Research

Table 3 Volume, average, and standard deviation values of the AD-DPs for larger brain regions

Region	Volume (cm³)	FDG	R₁	ePIB(20–130 s)	ePIB(1–8 min)
Brainstem	29.29	0.66 ± 0.33	0.41 ± 0.94	0.39 ± 0.63	0.19 ± 0.92
Frontal lobe	501.06	0.07 ± 1.05	0.05 ± 1.02	0.23 ± 0.77	0.26 ± 0.89
Occipital lobe	172.99	− 0.25 ± 0.76	− 0.11 ± 0.65	0.50 ± 0.79	0.36 ± 0.71
Parietal lobe	307.86	− 0.58 ± 1.23	− 0.41 ± 0.95	− 0.68 ± 1.01	0.00 ± 0.82
Temporal lobe	285.69	− 0.11 ± 0.81	− 0.23 ± 0.82	− 0.45 ± 0.84	0.03 ± 0.68
Cerebellum	180.89	0.73 ± 0.65	0.58 ± 0.89	0.77 ± 1.00	0.44 ± 0.83
Posterior cingulate cortex	6.38	− 1.30 ± 1.17	− 0.76 ± 0.91	− 1.16 ± 0.91	0.33 ± 0.82