Table 1 ⁶⁸Ga-NODAGA-BMS986192 Dosimetry Summary of Effective Doses in healthy male cynomolgus (mSv/MBq)

Adrenals

5.75E−04

6.41E−04

4.33E−04

5.50E−04

1.06E−04

Brain

3.25E−05

3.24E−05

2.90E−05

3.13E−05

1.99E−06

Cortical Bone

3.64E−06

5.69E−06

6.67E−06

5.33E−06

1.55E−06

Esophagus

3.25E−04

3.67E−04

3.09E−04

3.34E−04

3.00E−05

Eyes

0.00E+00

0.00E+00

0.00E+00

0.00E+00

0.00E+00

Gallbladder Wall

3.56E−04

2.34E−05

2.66E−04

2.15E−04

1.72E−04

Heart Contents

4.89E−05

2.21E−05

3.33E−05

3.48E−05

1.35E−05

Heart Wall

7.66E−06

4.32E−05

6.52E−05

3.87E−05

2.90E−05

Kidneys

1.03E−03

2.21E−03

1.16E−03

1.47E−03

6.47E−04

Liver

9.41E−04

7.31E−04

4.09E−04

6.94E−04

2.68E−04

Lungs

7.06E−05

5.06E−05

3.20E−05

5.11E−05

1.93E−05

Left colon

4.33E−04

3.98E−05

4.27E−04

3.00E−04

2.25E−04

Muscle

6.78E−06

3.21E−06

4.42E−06

4.80E−06

1.82E−06

Osteogenic Cells

3.22E−06

3.89E−06

2.27E−06

3.13E−06

8.14E−07

Pancreas

2.25E−04

2.37E−04

2.94E−04

2.52E−04

3.69E−05

Prostate

6.03E−05

7.99E−06

4.06E−05

3.63E−05

2.64E−05

Rectum

6.02E−05

4.43E−06

4.29E−05

3.58E−05

2.85E−05

Red Marrow

4.33E−06

7.29E−07

5.50E−07

1.87E−06

2.13E−06

Salivary Glands

3.02E−04

5.88E−05

3.23E−05

1.31E−04

1.49E−04

Small Intestine

4.23E−04

4.88E−05

4.54E−04

3.09E−04

2.26E−04

Spleen

1.75E−04

1.05E−04

5.44E−05

1.11E−04

6.06E−05

Stomach Contents

5.01E−05

5.87E−05

5.48E−05

5.45E−05

4.31E−06

Stomach Wall

3.67E−04

3.07E−05

4.01E−04

2.66E−04

2.05E−04

Testes

5.88E−05

5.45E−05

3.22E−05

4.85E−05

1.43E−05

Thymus

6.43E−04

5.55E−04

6.79E−04

6.26E−04

6.38E−05

Thyroid

8.43E−04

7.40E−04

5.25E−04

7.03E−04

1.62E−04

Urinary Bladder Contents

2.12E−05

1.13E−05

2.11E−05

1.79E−05

5.69E−06

Urinary Bladder Wall

2.35E−05

1.27E−05

2.20E−05

1.94E−05

5.85E−06

Total Body

7.09E−03

6.10E−03

5.83E−03

6.34E−03

6.63E−04