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EJNMMI Research
Fig. 3 | EJNMMI Research

Fig. 3

From: PET imaging of an optimized anti-PD-L1 probe 68Ga-NODAGA-BMS986192 in immunocompetent mice and non-human primates

Fig. 3

A Representative coronal slices PET images of two mice bearing bilateral hPD-L1+ hPD-L1-B16F10 (yellow arrows) and hPD-L1− B16F10 (blue arrows) tumors at 60 min post-68Ga-NODAGA-BMS986192 administration. The left images show probe alone; the right images show co-administration of 10 mg/kg ADX_5322_A02; B Representative time-activity curves; C Mice ex vivo biodistribution of 68Ga-NODAGA-BMS986192, 1 h and 2 h post-injection (n = 5/group); D Mice ex vivo biodistribution of.68Ga-NODAGA-BMS986192 1 h post-injection, with and without co-administration of cold ADX_5322_A02 as a blocking agent (n = 3/group)

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