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Table 1 Participant demographics

From: Impact of cerebral blood flow and amyloid load on SUVR bias

 

[18F]flutemetamol

[18F]florbetaben

All (N = 90)

Aβ-negative (N = 71)

Aβ-positive (N = 19)

All (N = 31)

Aβ-negative (N = 19)

Aβ-positive (N = 12)

Age

67.2 ± 6.3

66.2 ± 6.3**

70.7 ± 4.7

67.3 ± 7.4

66.0 ± 6.7

69.5 ± 8.2

Females %

54.4

57.7

42.1

67.7

73.7

58.3

MMSE

28.9 ± 1.4

29.2 ± 1.1

28.2 ± 2.1

29.1 ± 1.3

29.4 ± 0.8

28.7 ± 1.8

APOE-ε4 + %

41.6

34.3*

68.4

35.5

15.8*

66.7

SUVR

1.51 ± 0.3

1.41 ± 0.1**

1.86 ± 0.3

1.48 ± 0.2

1.36 ± 0.1**

1.66 ± 0.3

DVR

1.23 ± 0.1

1.18 ± 0.1**

1.41 ± 0.2

1.26 ± 0.2

1.18 ± 0.1**

1.40 ± 0.2

R1

1.00 ± 0.1

1.00 ± 0.1

0.97 ± 0.1

0.96 ± 0.2

0.96 ± 0.1

0.95 ± 0.1

Centre

A,B,C,D

A,B,C,D

A,B,C

A

A

A

Inj. dose (MBq)

186.2 ± 10.4

188.8 ± 10.1

184.0 ± 7.7

282.9 ± 19.7

284.4 ± 17.9

280.5 ± 22.9

  1. Values depicted as mean ± SD, MMSE = mini-mental state examination, Inj. dose = Net injected dose *p < 0.05, **p < 0.01, compared with the Aβ-positive group. A = Amsterdam UMC, B = BBRC, C = UNIGE, D = Edinburgh