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Table 1 Clinical features of 528 patients enrolled in this study

From: Development of a PET/CT molecular radiomics-clinical model to predict thoracic lymph node metastasis of invasive lung adenocarcinoma ≤ 3 cm in diameter

Clinical characteristics

Training (n = 371)

Testing (n = 157)

Lymph node (−)

Lymph node (+)

p value

Lymph node (−)

Lymph node (+)

p value

Age, year (median;IQR)

62; 55 ~ 67

62; 55 ~ 68

0.62

63; 56 ~ 69

60; 50 ~ 70

0.166

Gender

      

Male

103

46

0.369

48

23

0.555

Female

163

59

 

65

21

 

Smoke

      

Yes

84

36

0.617

38

15

0.958

No

182

69

 

75

29

 

Location

      

Upper lobe, right

109

30

0.024

48

12

0.101

Middle lobe, right

46

18

 

21

10

 

Lower lobe, right

13

8

 

5

1

 

Upper lobe, left

60

29

 

26

15

 

Lower lobe, left

38

20

 

13

6

 

CEA, ng/ml (median; IQR)

2.32; 1.53 ~ 3.93

3.67; 2.11 ~ 8.50

0.273

2.21; 1.53 ~ 3.52

3.59; 2.01 ~ 6.27

0.251

Lobulation

      

(+)

260

103

0.836

112

44

0.279

(−)

6

2

 

1

0

 

Burr

      

(+)

249

102

0.176

112

44

0.688

(−)

17

3

 

1

0

 

Pleural traction

      

(+)

45

53

< 0.001

15

18

< 0.001

(−)

221

52

 

98

26

 

Solid components, cm (median; IQR)

0.85; 0.50 ~ 1.3

2.05; 1.65 ~ 2.45

< 0.001

0.95; 0.55 ~ 1.4

2.1; 1.65 ~ 2.49

< 0.001

SUVmax (median;IQR)

3.68; 2.1 ~ 7.45

11.11; 8.92 ~ 15.31

0.145

3.57; 2.08 ~ 6.99

10.25; 7.1 ~ 13.36

0.279