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Table 5 [68Ga]NODAGA-RGDyK: M3 and M4 reassessed using αnew = 0.17

From: Comparison of absorbed dose extrapolation methods for mouse-to-human translation of radiolabelled macromolecules

Target Organ

Organ ADs (mGy/MBq) GA subject

M3

M4

Adrenals

1.30E−02

9.70E−03

Brain

4.96E−03

6.10E−03

Breasts

5.56E−03

6.62E−03

Oesophagus

6.43E−03

7.02E−03

Eyes

4.96E−03

6.10E−03

Gallbladder Wall

9.73E−03

8.52E−03

Left colon

2.55E−02

1.00E−02

Small Intestine

4.07E−02

1.43E−02

Stomach Wall

1.85E−02

8.92E−03

Right colon

2.60E−02

1.00E−02

Rectum

2.86E−02

1.36E−02

Heart Wall

9.02E−03

8.15E−03

Kidneys

5.10E−02

1.70E−02

Liver

3.14E−02

1.82E−02

Lungs

7.64E−03

1.17E−02

Ovaries

9.90E−03

1.05E−02

Pancreas

8.97E−03

8.05E−03

Prostate

9.52E−03

1.01E−02

Salivary Glands

5.24E−03

6.44E−03

Red Marrow

9.96E−03

9.34E−03

Osteogenic Cells

7.00E−03

6.96E−03

Spleen

2.19E−02

1.33E−02

Testes

5.60E−03

6.64E−03

Thymus

5.97E−03

7.19E−03

Thyroid

5.40E−03

6.60E−03

Urinary Bladder Wall

1.62E−01

1.63E−01

Uterus

1.37E−02

1.39E−02

Total Body

8.45E−03

8.45E−03

ED (mSv/MBq)

1.90E−02

1.52E−02