Table 1 Kinetic parameter estimates from the 1-tissue compartment model and Logan plot
Organ | V0 | K1 | k2 | Vt | CoV | AIC | Logan Vt | CoV | AIC |
|---|---|---|---|---|---|---|---|---|---|
Adrenal gland | 0.01 (0.001–0.08) | 0.59 (0.39–0.62) | 0.019 (0.007–0.021) | 33.1 (30.0–55.9) | 39% | 76 (19) | 29.9 (22.4–33.9) | 29% | 85 (13) |
- fixed V0 | 0.23 | 0.73 (0.58–0.77) | 0.018 (0.006–0.021) | 45.2 (35.7–83.1) | 47% | 91(13) | – |  |  |
Pancreas | 0.0035 (0.00023–0.051) | 1.00 (0.77–1.17) | 0.038 (0.033–0.046) | 24.3 (18.5–31.6) | 39% | 29 (26) | 23.6 (19.2–32.2) | 30% | 106 (17) |
- fixed V0 | 0.24 | 1.20 (1.00–1.49) | 0.038 (0.032–0.045) | 30.0 (23.0–41.1) | 32% | 49 (23) | – |  |  |
Myocardium | 0.13 (0.07–0.16) | 0.63 (0.54–0.78) | 0.027 (0.023–0.036) | 24.3 (17.8–32.0) | 34% | − 20 (28) | 21.9 (16.9–27.0) | 29% | 94 (39) |
Spleen | 0.17 (0.11–0.25) | 1.39 (1.20–1.72) | 0.12 (0.10–0.16) | 9.72 (9.15–12.7) | 26% | 2 (28) | 9.01 (8.03–10.5) | 20% | 105 (43) |
Renal cortex | 0.17 (0.14–0.22) | 1.73 (1.25–1.84) | 0.25 (0.23–0.27) | 6.06 (5.25–7.76) | 23% | 68 (53) | 6.17 (5.41–7.23) | 17% | 119 (39) |
Muscle | 0.0004 (0.00002- 0.004) | 0.049 (0.04–0.09) | 0.012 (0.009–0.016) | 4.20 (3.73–5.26) | 34% | 59 (30) | 4.22 (3.03–5.16) | 44% | 87 (18) |
- fixed V0 | 0.027 | 0.050 (0.04–0.10) | 0.01 (0.009–0.014) | 4.48 (3.92–5.51) | 28% | 87 (20) | – |  |  |
Colon | 0.027 (0.015–0.033) | 0.078 (0.063–0.1) | 0.030 (0.021–0.041) | 2.64 (1.94–3.51) | 37% | 97 (16) | 3.51 (2.61–4.2) | 29% | 82 (10) |