Fig. 1From: The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapySchematic illustration of NIS and its role in gene therapy. NIS is a powerful theranostic tool for diagnostic imaging and the application of therapeutic radionuclides. The transport of various radiotracers allows non-invasive monitoring of the in vivo biodistribution of functional NIS expression by whole body scintigraphy, SPECT or PET imaging and the application of therapeutically active radionuclides enables cytoreductive effectsBack to article page