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Table 3 Coefficients of determination (r2) and slope of parametric [11C]UCB-J DVR, BPND and R1 against corresponding SRTM estimates

From: Validation and test–retest repeatability performance of parametric methods for [11C]UCB-J PET

 

HC

AD

r2

Slope

r2

Slope

Reference Loganb DVR

0.82

0.78

0.83

0.75

RPMb BPND

0.92

1.00

0.97

1.02

RPMb R1

0.99

1.01

0.99

0.99

SRTM2b BPND

0.81

1.02

0.91

1.18

SRTM2b R1

0.98

1.01

0.97

1.01

MRTMo BPNDb

0.81

0.76

0.85

0.73

MRTMo b R1

0.40

0.70

0.34

0.67

MRTM1b BPND

0.85

0.91

0.87

0.83

MRTM1b R1

0.93

1.09

0.91

1.02

MRTM2b BPND

0.53

0.89

0.43

1.41

MRTM2b R1

0.93

1.10

0.94

1.02

MRT3b BPND

0.80

0.80

0.70

0.66

MRTM3b R1

0.02

0.11

0.00

0.05

MRTM4b BPND

0.87

1.01

0.60

1.06

MRTM4b R1

0.05

0.08

0.00

− 0.06

  1. BPND: binding potential; MRTM: multilinear reference tissue model; NLR: non-linear regression; RPM: receptor parametric mapping; SRTM2: simplified reference tissue model 2
  2. aPlasma input implementations
  3. bReference region implementations