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EJNMMI Research

Table 2 Coefficients of determination (r2) and slope of parametric [11C]UCB-J VT, K1 and BPND against corresponding 1T2k_VB estimates using 60 min data

From: Validation and test–retest repeatability performance of parametric methods for [11C]UCB-J PET

 

HC

AD

r2

Slope

r2

Slope

Spectral analysisa VT

0.88

0.85

0.93

0.95

Spectral analysis a K1

0.94

0.85

0.97

0.84

Logan a VT

0.90

0.74

0.94

0.83

Reference Loganb DVR

0.80

0.64

0.79

0.60

RPMb BPND

0.82

0.77

0.89

0.79

SRTM2b BPND

0.82

0.84

0.94

0.95

MRTMob BPND

0.79

0.62

0.76

0.57

MRTM1b BPND

0.83

0.75

0.77

0.64

MRTM2b BPND

0.59

0.78

0.40

1.13

MRTM3b BPND

0.75

0.64

0.63

0.51

MRTM4b BPND

0.85

0.81

0.56

0.87

  1. BPND: binding potential; MRTM: multilinear reference tissue model; NLR: non-linear regression; RPM: receptor parametric mapping; SRTM2: simplified reference tissue model 2.
  2. aPlasma input implementations
  3. bReference region implementations
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