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Table 2 Time-integrated activity coefficients (TIAC) for [18F]PR04.MZ for all subjects and

From: Whole-body biodistribution and radiation dosimetry of [18F]PR04.MZ: a new PET radiotracer for clinical management of patients with movement disorders

Organ TIAC (MBq h/MBq)
HC-01 (M) HC-02 (M) HC-03 (M) HC-04 (F) HC-05 (F) HC-06 (F) Mean StDev CoV (%)
Braina 5.59E−02 4.80E−02 4.00E−02 3.87E−02 4.61E−02 3.82E−02 4.45E−02 6.90E−03 15.5
Cortical bone mineral surfacea 2.97E−01 2.86E−01 3.53E−01 2.82E−01 2.13E−01 3.08E−01 2.90E−01 4.55E−02 15.7
Gallbladder contenta 3.34E−02 3.98E−02 3.93E−02 3.23E−02 1.95E−02 5.77E−03b 2.83E−02 1.33E−02 46.8
Heart contents 1.95E−02 2.34E−02 2.31E−02 1.73E−02 1.61E−02 2.29E−02 2.04E−02 3.21E−03 15.7
Heart walla 7.63E−03 8.15E−03 7.47E−03 6.72E−03 4.96E−03 5.76E−03 6.78E−03 1.22E−03 18.0
Kidneysa 2.85E−02 2.95E−02 2.59E−02 2.36E−02 2.54E−02 2.60E−02 2.65E−02 2.16E−03 8.1
Left colon contentsa 7.50E−02 8.30E−02 5.99E−02 6.34E−02 4.61E−02 4.44E−02 6.20E−02 1.54E−02 24.8
Livera 1.42E−01 1.45E−01 1.45E−01 1.41E−01 1.43E−01 1.12E−01 1.38E−01 1.28E−02 9.3
Lungsa 6.31E−02 4.01E−02 4.90E−02 3.82E−02 4.42E−02 5.25E−02 4.79E−02 9.19E−03 19.2
Pancreasa 1.17E−02 2.99E−03 4.19E−03 6.86E−03 6.15E−03 5.96E−03 6.31E−03 3.00E−03 47.6
Parotid glands 4.18E−03 5.44E−03 4.60E−03 5.72E−03 5.41E−03 2.27E−03 4.60E−03 1.28E−03 27.9
Red marrowa 2.44E−01 2.38E−01 2.08E−01 1.74E−01 1.92E−01 1.92E−01 2.08E−01 2.78E−02 13.4
Right colon contentsa 7.50E−02 8.30E−02 5.99E−02 6.34E−02 4.61E−02 4.44E−02 6.20E−02 1.54E−02 24.8
Spleena 4.40E−03 4.19E−03 7.09E−03 2.99E−03 2.88E−03 5.57E−03 4.52E−03 1.60E−03 35.5
Stomach contentsa 4.11E−02 1.89E−02 1.17E−02 3.43E−02 1.53E−02 4.92E−03 2.10E−02 1.39E−02 66.0
Submaxillary glands 3.01E−03 2.66E−03 3.16E−03 2.70E−03 3.01E−03 2.85E−03 2.90E−03 1.96E−04 6.8
Total bodya 2.19E + 00 2.40E + 00 2.28E + 00 2.28E + 00 2.24E + 00 2.32E + 00 2.29E + 00 7.15E−02 3.1
Trabecular bone mineral surfacea 7.41E−02 7.14E−02 8.82E−02 7.06E−02 5.33E−02 7.69E−02 7.24E−02 1.13E−02 15.6
Urinary bladder contenta 9.63E−02 1.19E−01 1.19E−01 1.14E−01 1.12E−01 4.54E−02 1.01E−01 2.85E−02 28.2
  1. aUsed as input for dose calculations in IDAC 2.1
  2. bSubject underwent cholecystectomy prior to inclusion—activity uptake from bile duct