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Table 2 Time-integrated activity coefficients (TIAC) for [18F]PR04.MZ for all subjects and

From: Whole-body biodistribution and radiation dosimetry of [18F]PR04.MZ: a new PET radiotracer for clinical management of patients with movement disorders

Organ

TIAC (MBq h/MBq)

HC-01 (M)

HC-02 (M)

HC-03 (M)

HC-04 (F)

HC-05 (F)

HC-06 (F)

Mean

StDev

CoV (%)

Braina

5.59E−02

4.80E−02

4.00E−02

3.87E−02

4.61E−02

3.82E−02

4.45E−02

6.90E−03

15.5

Cortical bone mineral surfacea

2.97E−01

2.86E−01

3.53E−01

2.82E−01

2.13E−01

3.08E−01

2.90E−01

4.55E−02

15.7

Gallbladder contenta

3.34E−02

3.98E−02

3.93E−02

3.23E−02

1.95E−02

5.77E−03b

2.83E−02

1.33E−02

46.8

Heart contents

1.95E−02

2.34E−02

2.31E−02

1.73E−02

1.61E−02

2.29E−02

2.04E−02

3.21E−03

15.7

Heart walla

7.63E−03

8.15E−03

7.47E−03

6.72E−03

4.96E−03

5.76E−03

6.78E−03

1.22E−03

18.0

Kidneysa

2.85E−02

2.95E−02

2.59E−02

2.36E−02

2.54E−02

2.60E−02

2.65E−02

2.16E−03

8.1

Left colon contentsa

7.50E−02

8.30E−02

5.99E−02

6.34E−02

4.61E−02

4.44E−02

6.20E−02

1.54E−02

24.8

Livera

1.42E−01

1.45E−01

1.45E−01

1.41E−01

1.43E−01

1.12E−01

1.38E−01

1.28E−02

9.3

Lungsa

6.31E−02

4.01E−02

4.90E−02

3.82E−02

4.42E−02

5.25E−02

4.79E−02

9.19E−03

19.2

Pancreasa

1.17E−02

2.99E−03

4.19E−03

6.86E−03

6.15E−03

5.96E−03

6.31E−03

3.00E−03

47.6

Parotid glands

4.18E−03

5.44E−03

4.60E−03

5.72E−03

5.41E−03

2.27E−03

4.60E−03

1.28E−03

27.9

Red marrowa

2.44E−01

2.38E−01

2.08E−01

1.74E−01

1.92E−01

1.92E−01

2.08E−01

2.78E−02

13.4

Right colon contentsa

7.50E−02

8.30E−02

5.99E−02

6.34E−02

4.61E−02

4.44E−02

6.20E−02

1.54E−02

24.8

Spleena

4.40E−03

4.19E−03

7.09E−03

2.99E−03

2.88E−03

5.57E−03

4.52E−03

1.60E−03

35.5

Stomach contentsa

4.11E−02

1.89E−02

1.17E−02

3.43E−02

1.53E−02

4.92E−03

2.10E−02

1.39E−02

66.0

Submaxillary glands

3.01E−03

2.66E−03

3.16E−03

2.70E−03

3.01E−03

2.85E−03

2.90E−03

1.96E−04

6.8

Total bodya

2.19E + 00

2.40E + 00

2.28E + 00

2.28E + 00

2.24E + 00

2.32E + 00

2.29E + 00

7.15E−02

3.1

Trabecular bone mineral surfacea

7.41E−02

7.14E−02

8.82E−02

7.06E−02

5.33E−02

7.69E−02

7.24E−02

1.13E−02

15.6

Urinary bladder contenta

9.63E−02

1.19E−01

1.19E−01

1.14E−01

1.12E−01

4.54E−02

1.01E−01

2.85E−02

28.2

  1. aUsed as input for dose calculations in IDAC 2.1
  2. bSubject underwent cholecystectomy prior to inclusion—activity uptake from bile duct