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Table 1 Time-integral of activity for accumulation in significant source organs (AUCs)

From: Preclinical biodistribution and dosimetry and human biodistribution comparing 18F-rhPSMA-7 and single isomer 18F-rhPSMA-7.3

  AUC (%IA/g) organ Heart Lung Liver Spleen Kidney
18F-rhPSMA-7 No extrapolation 0.17 ± 0.01 0.84 ± 0.04 0.78 ± 0.05 1.93 ± 0.13 6.39 ± 0.65
  Extrapolation + physical decay 0.18 ± 0.01 0.9 ± 0.04 0.87 ± 0.06 2.1 ± 0.13 10.12 ± 0.75
18F-rhPSMA-7.3 No extrapolation 0.29 ± 0.03 1.35 ± 0.12 1.25 ± 0.08 2.05 ± 0.2 8.99 ± 0.64
  Extrapolation + physical decay 0.3 ± 0.03 1.38 ± 0.12 1.33 ± 0.08 2.08 ± 0.2 10.8 ± 0.74
  1. AUC: area under the curve; %IA: %injected activity. AUC is presented ± standard deviation