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EJNMMI Research

Table 3 Magnetic nanoparticles in melanoma theranostics

From: Magnetic nanoparticles in theranostics of malignant melanoma

Nanoparticles   Method Mode of action Refs
Intrinsic properties Magnetic core Magnetic hyperthermia Induction of apoptosis [106]
Impaired cell differentiation and proliferation due to protein alteration [107–110]
Irreversible cell damage [68, 69]
Immunostimulation [45, 116, 117]
Photothermal therapy [121–124]
Magneto-mechanical effects Cell damage, apoptosis induction [128–130]
Damage of neovasculature [131]
Magnetoporation, magnetolysis [132, 133]
Localized magnetic field Drug release [134–138, 141–144]
Nanozyme Induction of ferroptosis [145–150]
Extrinsic properties Coating with attachments Release of chemotherapeutic agents Cytotoxicity, apoptosis [152–158]
Immunoadjuvants Immunostimulation [159, 165]
Tumor-targeting molecules   [143, 169]
Labels for imaging Diagnostics [172—175]
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