Skip to main content

Table 1 Demographics at group level

From: L-type amino acid transporter (LAT) 1 expression in 18F-FET-negative gliomas

 

18F-FET positive

18F-FET negative

Number of subjects

20

20

Age (y, median, range)

39.9 (25.9–69.3)

37.8 (26.3–47.6)

Sex (♀ /♂)

8♀/12♂

9♀/11♂

WHO grade

II

11

20

III

9

0

Mode of surgery

Biopsy

14

19

Resection

6

1

SUVBG (median, range)

1.04 (0.67–1.93)

1.01 (0.35–1.20)

SUVmax (median, range)

2.91 (1.32–5.75)

1.16 (0.40–1.81)

TBRmax (median, range)

2.29 (1.61–5.17)

1.24 (0.84–1.58)

SUVmean (median, range)

1.94 (1.19–3.09)

 

TBRmean (median, range)

1.93 (1.68–2.38)

 

BTV (median, range)

19.52 (1.38–78.46)

 

% LAT1-positive tumour cells by staining intensity (median, range)

0

70 (0–98)

80 (0–98)

1

20 (0–95)

10 (0–95)

2

5 (0–80)

5 (0–50)

LAT1 overall H-score (median, range)

22.5 (2–180)

25.5 (5–118)

LAT1 H-score tumour cells (median, range)

11.0 (0–180)

10.5 (0–84)

LAT1 H-score vessels (median, range)

6.5 (0–42)

4.5 (0–22)

  1. SUVmax = mean background uptake; SUVmax = maximal standardized uptake value; TBRmax = maximal tumour-to-background ratio; SUVmean = mean standardized uptake value (in 18F-FET-positive lesions only); TBRmean = mean tumour-to-background ratio (in 18F-FET-positive lesions only); BTV = biological tumour volume (in 18F-FET-positive lesions only); %LAT1-positive tumour cells by staining intensity show the percentage of cells with no (0), low (1), or high (2) staining intensity within tissue samples in the two groups of 18F-FET-positive and 18F-FET-negative gliomas