Fig. 1

Patient example with a A ¹⁸F-FET-positive, WHO grade II glioma with a high ¹⁸F-FET-uptake (TBR_max 4.36) and small nodular contrast enhancement on MRI but with very low LAT1 tumour cell expression (H-score 9.0) and slightly positive vessels in the SLC7A5 immunohistochemical (IHC) staining in contrast to a B ¹⁸F-FET-negative, WHO grade II glioma (TBR_max 1.27) with T2 alterations and missing contrast enhancement on MRI but a very high LAT1 expression (H-score 102.0) and intensive vessel staining