Dynamic planar scintigraphy for the rapid kinetic measurement of myocardial 123I-MIBG turnover can identify Lewy body disease

EJNMMI Research

Table 4 Kinetic results of the three-parameter model (1T3P)

1T3P	5 min	10 min	15 min	20 min	25 min	30 min	105 min	195 min
iUp	0.159	0.150	0.141	0.135	0.132	0.130	0.140	0.149
iUp	(0.092)	(0.077)	(0.070)	(0.066)	(0.064)	(0.063)	0.061	(0.057)
iLoss	0.058	0.067	0.059	0.054	0.051	0.050	0.061	0.071
iLoss	(0.121)	(0.032)	(0.020)	(0.018)	(0.017)	(0.017)	(0.027)	(0.038)
iNs	0.107	0.132	0.162	0.186	0.200	0.209	0.155	0.117
iNs	(0.133)	(0.112)	(0.108)	(0.110)	(0.112)	(0.113)	(0.129)	(0.165)
iUp/iLoss	1.92	2.76	2.65	2.93	3.05	3.10	3.01	3.00
iUp/iLoss	(2.65)	(4.52)	(1.85)	(1.84)	(1.93)	(1.99)	(2.01)	(2.03)
0.693/iLoss	7.3	16.6	10.5	14.1	14.8	15.2	13.5	12.8
0.693/iLoss	(18.2)	(77.9)	(23.8)	(4.2)	(4.3)	(4.4)	(5.5)	(6.3)
Akaike IC	− 203.7	− 287.9	− 360.5	− 428.4	− 494.1	− 558.5	− 551.1	− 551.9
Schwarz IC	− 198.6	− 281.9	− 353.8	− 421.0	− 486.3	− 550.3	− 542.8	− 543.5
iUp NegCnt	0	0	0	0	0	0	0	0
iLoss NegCnt	29	5	2	0	0	0	0	0
iNs NegCnt	42	25	11	8	7	3	16	51

Means (and SDs) of the kinetic indices of 1T3P, Akaike’s information criterion and Schwarz’s information criterion. NegCnt: negative counts that were unfavourable; 0.693/iLoss is the pharmacological half-life