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Table 6 Ki results obtained from static scan using the static scan analysis compared with Ki results obtained from dynamic scan using Patlak analysis

From: Comparison of [18F] NaF PET/CT dynamic analysis methods and a static analysis method including derivation of a semi-population input function for site-specific measurements of bone formation in a population with chronic kidney disease-mineral and bone disorder

Scan First and second exponentials Terminal exponential V0 (%) Ki
(ml min−1 ml−1)
Percentage difference p Value R p value
Dynamic, Patlak Population residual Blood samples 30–90 min 64 0.0346 ± 0.009
Static Population residual Blood samples 30–60 min 43 0.0399 ± 0.010  + 15%  < 0.001* 0.930  < 0.001*
52 0.0390 ± 0.010  + 13% 0.002* 0.931  < 0.001*
Static Population residual Blood samples 30–90 min 43 0.0419 ± 0.011  + 21%  < 0.001* 0.940  < 0.001*
64 0.0395 ± 0.011  + 14% 0.001* 0.942  < 0.001*
  1. Mean values ± SD are presented from 12 scans (Th7–10). Three different assumptions of V0 are applied and compared with Patlak analysis Ki values obtained using dynamic scans. Pearson’s correlation coefficient (R), *Level of statistical significance: p < 0.05