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EJNMMI Research

Table 3 Comparison input functions obtained by β-corrected image-derived arterial input functions (IDAIF) and semi-population input functions

From: Comparison of [18F] NaF PET/CT dynamic analysis methods and a static analysis method including derivation of a semi-population input function for site-specific measurements of bone formation in a population with chronic kidney disease-mineral and bone disorder

 

IDAIF

β-corrected and blood samples

(30–60 min)

SPIF

Population residual and blood samples

(30–60 min)

IDAIF

β-corrected and blood samples

(30–90 min)

SPIF

Population residual and blood samples

(30–90 min)

AUC ± SD

353 ± 59

348 ± 74

341 ± 54

331 ± 70

Percentage difference (p value)

 

 − 1.4% (0.671)

 

 − 2.9% (0.315)

  1. The data are presented as mean values ± SD obtained by the same 12 scans. AUC area under the curve. Level of statistical significance is p < 0.05
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