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Table 3 Comparison input functions obtained by β-corrected image-derived arterial input functions (IDAIF) and semi-population input functions

From: Comparison of [18F] NaF PET/CT dynamic analysis methods and a static analysis method including derivation of a semi-population input function for site-specific measurements of bone formation in a population with chronic kidney disease-mineral and bone disorder

  IDAIF
β-corrected and blood samples
(30–60 min)
SPIF
Population residual and blood samples
(30–60 min)
IDAIF
β-corrected and blood samples
(30–90 min)
SPIF
Population residual and blood samples
(30–90 min)
AUC ± SD 353 ± 59 348 ± 74 341 ± 54 331 ± 70
Percentage difference (p value)    − 1.4% (0.671)    − 2.9% (0.315)
  1. The data are presented as mean values ± SD obtained by the same 12 scans. AUC area under the curve. Level of statistical significance is p < 0.05