Fig. 4

A A VOI placed in LV and a myocardial VOI for β-correction. B FOV from a dynamic 18F-NaF PET/CT showing VOIs to obtain bone TACs in vertebrae Th7–10 and a VOI in the left ventricle of the heart (LV) to obtain the image-derived input function. C Whole-body 18F-NaF PET/CT with the possibility to make bone VOIs in the entire skeleton