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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer

Fig. 1

SPR analysis of anti-huLAG-3 sdAbs. A The table shows the code, sequence family and affinity of the sixteen selected sdAbs as determined by SPR on immobilized huLAG-3-Fc. B RaPID plot illustrating the association (ka) and dissociation (kd) values for each of the sdAbs, determined via affinity analysis using the biacore T100 instrument. Each sdAb, color-coded for family-homology, is indicated as a dot on the two-dimensional graph so that pairings with identical affinity (KD) values are located along iso-affinity diagonals

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