Fig. 5From: Dose escalation biodistribution, positron emission tomography/computed tomography imaging and dosimetry of a highly specific radionuclide-labeled non-blocking nanobodyRadioactivity in the ROI in images of the male cynomolgus monkeys was quantified as SUV mean. a Time-activity curves of the spleen, heart, liver, lungs, muscles, bones, stomach, and brain. b Time-activity curves of the kidneys and urinary bladder. c Spleen-to-organ (heart, liver, lungs, muscles, bones, and stomach) ratio curves at different time intervals. d Effective dose estimation from cynomolgus monkeys to adult humans (mSv/MBq); data of each organ shows the total effective doseBack to article page