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Table 2 PET/CT results after application of IMPeTUs

From: The prognostic significance of [18F]FDG PET/CT in multiple myeloma according to novel interpretation criteria (IMPeTUs)

IMPeTUs criteria

Baseline PET/CT (n = 47)

Patients (%)§

Follow-up PET/CT (n = 34)

Patients (%)§

 

Bone marrow uptake, DS

   

1

0

0

 

2

7 (15%)

13 (38%)

 

3

19 (40%)

19 (56%)

 

4

18 (38%)

2 (6%)

 

5

3 (6%)

0

 

No. of focal, hypermetabolic lesions

   

F1 (none)

11 (23%)

21 (62%)

 

F2 (1–3)

15 (32%)

8 (24%)

 

F3 (4–10)

9 (19%)

3 (9%)

 

F4 (> 10)

12 (26%)

2 (6%)

 

Site of focal lesions*

   

Skull

2 (4%)

1 (3%)

 

Spine

23 (49%)

3 (9%)

 

Other

33 (70%)

12 (35%)

 

Uptake of the hottest focal lesion, DS

 

Approach 1

Approach 2

1

0

0

2 (8%)

2

0

1 (8%)

9 (35%)

3

1 (3%)

0

5 (19%)

4

14 (39%)

7 (54%)

7 (27%)

5

21 (58%)

5 (39%)

3 (12%)

No. of lytic lesions

   

L1 (none)

8 (17%)

5 (15%)

 

L2 (1–3)

12 (26%)

9 (27%)

 

L3 (4–10)

7 (15%)

5 (15%)

 

L4 (> 10)

20 (43%)

15 (44%)

 

Presence of at least one fracture

   

No

25 (53%)

10 (29%)

 

Yes

22 (47%)

24 (71%)

 

Presence of PMD*

   

No

24 (51%)

34 (100%)

 

Yes

23 (49%)

0

 

Presence of EMD*

   

No

43 (92%)

30 (88%)

 

Yes

4 (9%)

4 (12%)

 
  1. *Measurements refer to hypermetabolic lesions
  2. §Due to rounding, the % percentage values do not necessarily add to 100%