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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: There is a world beyond αvβ3-integrin: Multimeric ligands for imaging of the integrin subtypes αvβ6, αvβ8, αvβ3, and α5β1 by positron emission tomography

Fig. 1

The integrin receptor family: Integrin subunits and the known dimers formed. Each connecting line represents one integrin. Although small-molecule ligands have been developed for many subtypes, radiolabeled derivatives thereof were reported only for a fraction of integrins (blue and red lines). "Clinical translation" encompasses all hitherto reported applications of such radiopharmaceuticals in humans, i.e., not only clinical trials but also single cases and small cohorts

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