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Fig. 5 | EJNMMI Research

Fig. 5

From: Evaluation of intracellular processes in quinolinic acid-induced brain damage by imaging reactive oxygen species generation and mitochondrial complex I activity

Fig. 5

Nissl-stained brain slices within the striatum after the acquisition of ex vivo fluorescent images. QA was injected into the striatum, and saline was simultaneously injected into the contralateral striatum. Three hours (A–C) or 24 h (D and E) after QA or saline injection. Neuronal degradation was observed in the greyed-out area within an approximately 1.0-mm-diameter area (B) and in the whole striatum (E). The red hatched area corresponds to the area of increased fluorescence signal. The images in A, C, and D showed no abnormalities. Bar = 100 µm

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