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EJNMMI Research

Table 2 Phantom experiments: LSF in planar imaging vs. SPECT/CT (with % SD from actual LSF in parenthesis)

From: Lung shunt fraction calculation using 99mTc-MAA SPECT/CT imaging for 90Y microsphere selective internal radiation therapy of liver tumors

Exp

Lung

KBq/mL

Liver

KBq/mL

Actual LSF

2D LSF

3D LSF AC

3D LSF noAC

1

0.57

25.78

3.58%

4.40%

(22.9%)

3.88%

(8.4%)

4.05%

(13.1%)

2

2.24

60.03

5.85%

7.60%

(29.9%)

6.35%

(8.5%)

6.82%

(16.6%)

3

5.77

122.10

7.30%

9.30%

(27.4%)

7.78%

(6.6%)

8.24%

(12.9%)

4

7.47

123.30

9.21%

11.50%

(24.9%)

9.48%

(2.9%)

10.42%

(13.3%)

5

8.94

146.15

9.23%

11.70%

(26.8%)

9.68%

(4.9%)

10.39%

(12.6%)

6

11.32

157.40

10.70%

13.40%

(25.2%)

11.45%

(7.0%)

12.57%

(17.5%)

  1. Volumes: L Lung = 900 mL, R Lung = 1100 mL, Liver = 1200 mL
  2. Range of Injected Activity: Lungs: (1.15–22.64) MBq; Liver: (30.93–188.89 MBq)
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