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Fig. 5 | EJNMMI Research

Fig. 5

From: [123I]MIBG is a better early marker of anthracycline cardiotoxicity than [18F]FDG: a preclinical SPECT/CT and simultaneous PET/MR study

Fig. 5

Evaluation of cardiac [123I]MIBG uptake in vehicle and doxorubicin-treated rats measured on SPECT images. a, b Cardiac [123I]MIBG uptake monitoring during the 6 weeks of experimental protocol. Data are expressed as heart to mediastinum (H to M) ratio related to control group (a) and H to M ratio (b) and as mean ± SEM. p values presented on graphs are comparisons between control and doxorubicin groups. c Representative cardiac-centered coronal views of [123I]MIBG SPECT-CT images in control (upper panel) and doxorubicin-treated rats (lower panel) obtained at 6 weeks

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