Table 2 The organ of distant biopsy and the corresponding immunohistochemical profile of metastatic lesions and the distribution of metastatic sites, organ involvement, and burden of the disease appear among 52 women diagnosed with metastatic breast cancer by [18F]FDG-PET/CT
Characteristics | Biopsy | [18F]FDG-PET/CT |
|---|---|---|
n (%) | n (%) | |
Organ of biopsy | ||
Bone | 20 (38.5) | N/A |
Lymph node | 11 (21.2) | |
Liver | 7 (13.5) | |
Lung and pleural fluid | 5 (9.62) | |
Breast* (local recurrence) | 4 (7.69) | |
Other† | 5 (9.62) | |
ER status | ||
Negative (0%) | 7 (13.5) | N/A |
Positive (1–100%) | 43 (82.7) | |
Unknown | 2 (3.85) | |
HER-2 status | ||
Normal | 46 (88.5) | |
Positive | 1 (1.92) | |
Unknown | 5 (9.62) | |
Location of distant metastases# | ||
Bone | N/A | 39 (75.0) |
Lung incl. pleural fluid or pleural metastases | 30 (57.7) | |
Lymph node‡ | 28 (53.9) | |
Liver | 16 (30.8) | |
Other | 7 (13.5) | |
Skin/subcutis | 3 (5.78) | |
CNS | 3 (5.78) | |
Organ involvement | ||
Bone-only§ | N/A | 15 (28.8) |
Visceral | 16 (30.8) | |
Lymph node only | 2 (3.85) | |
Mixed | 19 (36.5) | |
Number of distant metastases | ||
1 | N/A | 0 (0.00) |
2–4 | 8 (15.4) | |
≥ 5 | 44 (84.6) | |
Total | 52 (100) | 52 (100) |