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Table 1 Primary characteristics of patients and controls

From: Investigation of spleen CXCR4 expression by [68Ga]Pentixafor PET in a cohort of 145 solid cancer patients

Entity

n

Male (n/%)

Female (n/%)

Age (mean ± SD)

Stage limited/advanced/unknown (n/%)

All tumors

145

89 (61.4%)

56 (38.6%)

58.8 ± 14.70

28 (19.3%)/62 (42.8%)/55 (37.9%)

 Adrenal cancers

31

13 (41.9%)

18 (58.1%)

51.3 ± 9.97

5 (16.1%)/19 (61.3%)/7 (22.6%)

 Atypical carcinoid of lung

1

0 (0.0%)

1 (100.0%)

58.0 ± 0.00

0 (0.0%)/0 (0.0%)/1 (100.0%)

 Breast cancer (non-neuroendocrine)

2

0 (0.0%)

2 (100.0%)

59.5 ± 1.50

0 (0.0%)/0 (0.0%)/2 (100.0%)

 Cholangiocarcinoma

4

3 (75.0%)

1 (25.0%)

70.3 ± 5.17

1 (25.0%)/2 (50.0%)/1 (25.0%)

 Colorectal cancer

1

1 (100.0%)

0 (0.0%)

60.0 ± 0.00

1 (100.0%)/0 (0.0%)/0 (0.0%)

 CUP (non-neuroendocrine)

3

1 (33.3%)

2 (66.7%)

74.3 ± 8.06

0 (0.0%)/2 (66.7%)/1 (33.3%)

 DSRCT

9

9 (100.0%)

0 (0.0%)

29.4 ± 8.90

0 (0.0%)/0 (0.0%)/9 (100.0%)

 Ewing’s sarcoma

1

1 (100.0%)

0 (0.0%)

53.0 ± 0.00

0 (0.0%)/1 (100.0%)/0 (0.0%)

 Granulosa cell tumor

1

0 (0.0%)

1 (100.0%)

72.0 ± 0.00

1 (100.0%)/0 (0.0%)/0 (0.0%)

 Hepatocellular carcinoma

6

3 (50.0%)

3 (50.0%)

61.3 ± 7.16

3 (50.0%)/1 (16.7%)/2 (33.3%)

 Laryngeal cancer

1

1 (100.0%)

0 (0.0%)

72.0 ± 0.00

0 (0.0%)/0 (0.0%)/1 (100.0%)

 Malignant paraganglioma

1

1 (100.0%)

0 (0.0%)

49.0 ± 0.00

0 (0.0%)/1 (100.0%)/0 (0.0%)

 MANEC

2

1 (50.0%)

1 (50.0%)

65.5 ± 2.50

0 (0.0%)/2 (100.0%)/0 (0.0%)

 Melanoma

2

2 (100.0%)

0 (0.0%)

66.0 ± 4.00

0 (0.0%)/0 (0.0%)/2 (100.0%)

 Mesothelioma

6

5 (83.3%)

1 (16.7%)

69.3 ± 9.59

1 (16.7%)/2 (33.3%)/3 (50.0%)

 Neuroendocrine tumors

25

17 (68.0%)

8 (32.0%)

66.3 ± 10.57

3 (12.0%)/14 (56.0%)/8 (32.0%)

 NSCLC

9

8 (88.9%)

1 (11.1%)

59.3 ± 8.56

4 (44.4%)/5 (55.6%)/0 (0.0%)

 Osteosarcoma

1

1 (100.0%)

0 (0.0%)

32.0 ± 0.00

1 (100.0%)/0 (0.0%)/0 (0.0%)

 Ovarial cancer

1

0 (0.0%)

1 (100.0%)

73.0 ± 0.00

1 (100.0%)/0 (0.0%)/0 (0.0%)

 Pancreatic adenocarcinoma

9

6 (66.7%)

3 (33.3%)

65.3 ± 12.89

2 (22.2%)/1 (11.1%)/6 (66.7%)

 Prostate cancer

2

2 (100.0%)

0 (0.0%)

64.0 ± 8.00

0 (0.0%)/1 (50.0%)/1 (50.0%)

 Renal cell carcinoma

4

3 (75.0%)

1 (25.0%)

71.8 ± 12.75

1 (25.0%)/2 (50.0%)/1 (25.0%)

 Sarcoma

7

3 (42.9%)

4 (57.1%)

45.7 ± 18.90

2 (28.6%)/1 (14.3%)/4 (57.1%)

 Salivary gland cancer

1

1 (100.0%)

0 (0.0%)

52.0 ± 0.00

0 (0.0%)/0 (0.0%)/1 (100.0%)

 SCLC

13

6 (46.2%)

7 (53.8%)

62.2 ± 11.41

2 (15.4%)/7 (53.8%)/4 (30.8%)

 Thyroid cancer

1

1 (100.0%)

0 (0.0%)

61.0 ± 0.00

0 (0.0%)/1 (100.0%)/0 (0.0%)

 Undifferentiated cancer of thymus

1

0 (0.0%)

1 (100.0%)

41.0 ± 0.00

0 (0.0%)/0 (0.0%)/1 (100.0%)

Controls

 Conn’s adenom

3

3 (100.0%)

0 (0.0%)

57.7 ± 7.93

n.a

 Healthy controls

2

1 (50.0%)

1 (50.0%)

65.5 ± 2.50

n.a

  1. Table indicates the number of patients and control patients (n) separated by type of tumor entity, indicating the respective number and frequency of male and female patients (n/%), mean age of patients in years (mean ± SD) as well as the number and frequency of patients with limited, advanced and unknown tumor stage (n/%)