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Table 1 Study demographics of the included papers reporting on preoperative functional nuclear medicine imaging and morphological volumetric imaging with computed tomography or magnetic resonance imaging for the prediction of mortality and/or liver failure

From: Comparison of nuclear imaging techniques and volumetric imaging for the prediction of postoperative mortality and liver failure in patients undergoing localized liver-directed treatments: a systematic review

Author Year Country Prospective study Consecutive recruitment Tracer Patients (n) Postoperative outcome Major/minor surgery or both Morphological volume assessment, CT/MRI Preoperative, combined preoperative/peroperative volumetric measurement or both Combined volumetric/ functional (NMI) parameter
Mortality Liver failure
Chapelle et al. [18] 2016 Belgium Yes Yes [99mTc]Tc-Meb 88 Yes Yes Both MRI Preoperative Yes
Chapelle et al. [27] 2017 Belgium Yes Yes [99mTc]Tc-Meb 188a Yes Yes Both MRI Preoperative Yes
Chapelle et al. [26] 2017 Belgium No Yes [99mTc]Tc-Meb 140 No Yes Both MRI Preoperative Yes
Cho et al. [14] 2017 Korea No Yes [18F]FDG 149 No Yes Both CT Preoperative Yes
Cieslak et al. [21] 2016 The Netherlands No Yes [99mTc]Tc-Meb 163 Yes Yes Major CT Preoperative No
de Graaf et al. [10] 2010 The Netherlands No Yes [99mTc]Tc-Meb 55 No Yes Major CT Preoperative No
Dinant et al. [19] 2007 The Netherlands Yes Yes [99mTc]Tc-Meb 46 Yes Yes Both CT Preoperative No
Fujioka et al. [33] 1999 Japan No No [99mTc]Tc-GSA 15 Yes No Both CT Preoperative No
Hayashi et al. [20] 2015 Japan No Yes [99mTc]Tc-GSA 133 Yes Yes Major CT Preoperative No
Hirai et al. [24] 2003 Japan No Yes [99mTc]Tc-GSA 30 No Yes Major CT Preoperative No
Kokudo et al. [17] 2002 Japan No Yes [99mTc]Tc-GSA 111 No Yes Minor CT Combined Yes
Kwon et al. [34] 2001 Japan No Yes [99mTc]Tc-GSA 47 Yes No Bothb CT Preoperative No
Kwon et al. [35] 2004 Japan No No [99mTc]Tc-GSA 32 Yes No Both CT Preoperative No
Kwon et al. [36] 2006 Japan No Yes [99mTc]Tc-GSA 178 Yes No Bothb CT Preoperative No
Nanashima et al. [32] 2007 Japan No Yes [99mTc]Tc-GSA 185 No Yes Both CT Preoperativec No
Nanashima et al. [37] 2013 Japan No No [99mTc]Tc-GSA 67 No Yes Bothb CT Preoperative No
Okabe et al. [30] 2014 Japan Yes Yes [99mTc]Tc-GSA 625 No Yes Bothb CT Preoperative No
Olthof et al. [22] 2017 The Netherlands No Yes [99mTc]Tc-Meb 116 Yes Yes Major CT Preoperative No
Otsuki et al. [15] 1997 Japan Yes No [11C]C-Met 11 Yes No Major CT Preoperative Yes
Rassam et al. [23] 2019 The Netherlands No Yes [99mTc]Tc-Meb 71 Yes Yes Both CT Preoperative No
Serenari et al.[6, 28] 2018 Argentina No Yes [99mTc]Tc-Meb 20 No Yes Major CT or MRI Preoperative No
Serenari et al. [29] 2019 Italy No Yes [99mTc]Tc-Meb 27 No Yes Major CT Preoperative No
Truant et al. [38] 2017 France Yes Yes [99mTc]Tc-Meb 100 Yes No Major CT Preoperative No
Yoshida et al. [31] 2012 Japan No No [99mTc]Tc-GSA 256 No Yes Both CT Preoperative Yes
Yumoto et al. [16] 2010 Japan No Yes [99mTc]Tc-GSA 101 No Yes Both CT Both No
  1. NMI: nuclear medicine imaging; CT: computed tomography; MRI: magnetic resonance imaging; [99mTc]Tc-Meb: 99mTc-labeled mebrofenin; [99mTc]Tc-GSA: 99mTc-labeled galactosyl human serum albumin; [18F]FDG: [18F]fluorodeoxyglucose; and [11C]C-Met: L-[methyl-11C]-methionine
  2. aIncluding 88 patients from a prior study from Chapelle et al. [18]
  3. bBoth major and minor surgery but analyzed separately in the paper
  4. cBased on the description in the paper, it is somewhat uncertain, whether the volumetric CT parameter was determined pre- or perioperatively. Here, we have assumed that the volumetric parameter was estimated with CT preoperatively