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Table 4 Multivariate analysis of risk factors of overall survival and progression-free survival

From: Prognostic value of baseline total metabolic tumour volume of 18F-FDG PET/CT imaging in patients with angioimmunoblastic T-cell lymphoma

  Characteristics HR (95% CI) p Characteristics HR (95% CI) p
OS TMTV > 514.6 cm3 2.586 (1.174–5.696) 0.018 TLG > 2141.0
  Low albumin Low albumin
  Low PLT Low PLT
  BMB positive BMB positive
  ECOG-PS > 1 2.826 (1.285–6.216) 0.010 ECOG-PS > 1 3.652 (1.714–7.781) 0.001
  B symptoms B symptoms
PFS TMTV > 514.6 cm3 2.333 (1.205–4.516) 0.012 TLG > 2141.0a
  Low PLT 2.425 (1.283–4.584) 0.006 Low PLT 2.053 (1.029–4.095) 0.041
  BMB positive BMB positive
  Age > 60 Age > 60
  ECOG-PS > 1 ECOG-PS > 1 2.107 (0.976–4.547) 0.058
  B symptoms B symptoms
  1. PFS, progression-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; ECOG-PS, Eastern Cooperative Oncology Group Performance Status; PLT, platelet; BMB, bone marrow biopsy; TMTV, total metabolic tumour volume; TLG, total lesion glycolysis
  2. aTMTV and TLG were separately incorporated into multivariate survival analysis due to the correlation between TMTV and TLG