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Table 3 Univariate regression survival analysis for survival and disease progression

From: Prognostic value of baseline total metabolic tumour volume of 18F-FDG PET/CT imaging in patients with angioimmunoblastic T-cell lymphoma

Characteristics

1-year PFS rate (%)

HR (95%CI)

p

3-year OS rate (%)

HR (95%CI)

p

Sex

      

 Female

56.5

  

48.1

  

 Male

33.3

1.445 (0.758–2.756)

0.264

44.5

1.153 (0.559–2.380)

0.699

Age

      

 ≤ 60

65.0

  

63.5

  

 > 60

30.6

2.189 (1.080–4.435)

0.030

36.2

2.062 (0.937–4.537)

0.072

B symptoms

      

 No

60.0

  

66.9

  

  Yes

33.3

2.038 (1.007–4.123)

0.048

33.9

2.412 (1.034–5.627)

0.042

Ann Arbor stage

      

 II/III

50.0

  

55.4

  

 IV

35.7

1.401 (0.749–2.620)

0.291

37.5

1.537 (0.751–3.144)

0.239

IPI

      

  0–2

40.0

  

50.6

  

  3–5

45.2

0.712 (0.381–1.331)

0.288

42.6

0.550 (0.270–1.121)

0.100

PIT

      

 0–1

55.6

  

 61.9

  

 2–4

20.0

2.543 (1.335–4.845)

0.005

18.0

3.101 (1.521–6.322)

0.002

ECOG-PS

      

  ≤ 1

51.2

  

55.7

  

 > 1

15.4

2.915 (1.442–5.890)

0.003

11.5

3.652 (1.714–7.781)

0.001

LDH

      

 Normal

42.9

  

64.3

  

 Elevated

42.9

1.279 (0.586–2.790)

0.536

40.4

1.664 (0.638–4.341)

0.298

β2-MG

      

  Normal

35.0

  

49.5

  

 Elevated

47.2

0.755 (0.394–1.445)

0.396

44.7

0.996 (0.467–2.125)

0.991

PLT

      

  Normal

19.0

  

60.7

  

  Low

57.1

2.585 (1.378–4.849)

0.003

22.2

3.018 (1.480–6.151)

0.002

Albumin

      

 Normal

46.7

  

62.0

  

 Low

41.5

0.917 (0.466–1.806)

0.802

40.2

2.710 (1.034–7.104)

0.043

BMB

      

 Negative

51.2

  

52.9

  

  Positive

15.4

2.384 (1.207–4.708)

0.012

23.1

2.298 (1.092–4.838)

0.028

Extranodal sites > 1

      

 No

44.7

  

46.5

  

  Yes

33.3

1.089 (0.471–2.515)

0.842

44.4

1.380 (0.564–3.375)

0.480

SUVmax

      

 ≤ 17.3

50.0

  

44.4

  

 > 17.3

35.7

1.296 (0.695–2.419)

0.415

47.4

0.925 (0.455–1.878)

0.828

TMTV (cm3)

      

 ≤ 514.6

58.6

  

66.9

  

 > 514.6

25.9

2.481 (1.295–4.754)

0.006

22.6

3.314 (1.476–6.655)

0.003

TLG

      

 ≤ 2141.0

61.5

  

66.6

  

 > 2141.0

26.7

2.351 (1.226–4.509)

0.010

27.6

2.543 (1.193–5.421)

0.016

  1. IPI, international prognostic index; PIT, prognostic index for T-cell lymphoma, ECOG-PS, Eastern Cooperative Oncology Group Performance Status; LDH, lactate dehydrogenase; β2-MG, β2-microglobulin, PLT, platelet, BMB, bone marrow biopsy, SUVmax, maximum standard uptake value; TMTV, total metabolic tumour volume, TLG, total lesion glycolysis