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Table 3 Univariate regression survival analysis for survival and disease progression

From: Prognostic value of baseline total metabolic tumour volume of 18F-FDG PET/CT imaging in patients with angioimmunoblastic T-cell lymphoma

Characteristics 1-year PFS rate (%) HR (95%CI) p 3-year OS rate (%) HR (95%CI) p
Sex       
 Female 56.5    48.1   
 Male 33.3 1.445 (0.758–2.756) 0.264 44.5 1.153 (0.559–2.380) 0.699
Age       
 ≤ 60 65.0    63.5   
 > 60 30.6 2.189 (1.080–4.435) 0.030 36.2 2.062 (0.937–4.537) 0.072
B symptoms       
 No 60.0    66.9   
  Yes 33.3 2.038 (1.007–4.123) 0.048 33.9 2.412 (1.034–5.627) 0.042
Ann Arbor stage       
 II/III 50.0    55.4   
 IV 35.7 1.401 (0.749–2.620) 0.291 37.5 1.537 (0.751–3.144) 0.239
IPI       
  0–2 40.0    50.6   
  3–5 45.2 0.712 (0.381–1.331) 0.288 42.6 0.550 (0.270–1.121) 0.100
PIT       
 0–1 55.6     61.9   
 2–4 20.0 2.543 (1.335–4.845) 0.005 18.0 3.101 (1.521–6.322) 0.002
ECOG-PS       
  ≤ 1 51.2    55.7   
 > 1 15.4 2.915 (1.442–5.890) 0.003 11.5 3.652 (1.714–7.781) 0.001
LDH       
 Normal 42.9    64.3   
 Elevated 42.9 1.279 (0.586–2.790) 0.536 40.4 1.664 (0.638–4.341) 0.298
β2-MG       
  Normal 35.0    49.5   
 Elevated 47.2 0.755 (0.394–1.445) 0.396 44.7 0.996 (0.467–2.125) 0.991
PLT       
  Normal 19.0    60.7   
  Low 57.1 2.585 (1.378–4.849) 0.003 22.2 3.018 (1.480–6.151) 0.002
Albumin       
 Normal 46.7    62.0   
 Low 41.5 0.917 (0.466–1.806) 0.802 40.2 2.710 (1.034–7.104) 0.043
BMB       
 Negative 51.2    52.9   
  Positive 15.4 2.384 (1.207–4.708) 0.012 23.1 2.298 (1.092–4.838) 0.028
Extranodal sites > 1       
 No 44.7    46.5   
  Yes 33.3 1.089 (0.471–2.515) 0.842 44.4 1.380 (0.564–3.375) 0.480
SUVmax       
 ≤ 17.3 50.0    44.4   
 > 17.3 35.7 1.296 (0.695–2.419) 0.415 47.4 0.925 (0.455–1.878) 0.828
TMTV (cm3)       
 ≤ 514.6 58.6    66.9   
 > 514.6 25.9 2.481 (1.295–4.754) 0.006 22.6 3.314 (1.476–6.655) 0.003
TLG       
 ≤ 2141.0 61.5    66.6   
 > 2141.0 26.7 2.351 (1.226–4.509) 0.010 27.6 2.543 (1.193–5.421) 0.016
  1. IPI, international prognostic index; PIT, prognostic index for T-cell lymphoma, ECOG-PS, Eastern Cooperative Oncology Group Performance Status; LDH, lactate dehydrogenase; β2-MG, β2-microglobulin, PLT, platelet, BMB, bone marrow biopsy, SUVmax, maximum standard uptake value; TMTV, total metabolic tumour volume, TLG, total lesion glycolysis