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Table 1 Baseline characteristics for 140 patients

From: Hematologic safety of 177Lu-PSMA-617 radioligand therapy in patients with metastatic castration-resistant prostate cancer

 

All patients (n = 140)

Age

72 (67–78)

PSA (µg/L)

86 (12–258)

Hemoglobin (g/dL)

11.9 (10.4–13.2)

White blood cells (109/L)

6.4 (5.0–7.8)

Platelets (109/L)

238 (188–286)

eGFR (mL/min/1.73 m2)

81.8 (68.0–93.7)

Alkaline phosphatase (U/L)

93 (67–200)

LDH (U/L)

240 (205–303)

Gleason score*

 

  < 8

42 (34)

  ≥ 8

82 (66)

ECOG performance status

 

 0

42 (30)

 1

81 (58)

 2

17 (12)

Sites of metastases

 

 Bone

125 (89)

  Uni-/oligo-/multifocal

48 (34)

  Disseminated/diffuse

77 (55)

 Lymph nodes

125 (89)

 Visceral

33 (24)

Previous mCRPC therapies

 

 Abiraterone

87 (62)

 Enzalutamide

75 (54)

 223Radium-dichloride

45 (32)

 Docetaxel

70 (50)

 Cabazitaxel

27 (19)

 Other chemotherapies

7 (5)

 EBRT (bone metastases)

49 (35)

  1. Data presented as median with interquartile range (IQR) or n (%)
  2. ECOG Eastern Cooperative Oncology Group, PSA prostate-specific antigen, eGFR estimated glomerular filtration rate, LDH lactate dehydrogenase, EBRT external beam radiotherapy
  3. *For available patients (n = 124), †: cisplatin, 5-FU, carboplatin, mitoxandrone