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Table 1 Patient characteristics [18F]-FDG-PET/MRI parameters and results of further staging examinations

From: Whole-body [18F]-FDG-PET/MRI for staging of pediatric non-Hodgkin lymphoma: first results from a single-center evaluation

Pat Age Histology ENTclin TC LP BMB USabdomen 18F-FDGadm 18F-FDGrecom Δinject/scan Sedation Images performed Result of PET/MR scan Figure
1 15 years Burkitt n.d n.d Splenomegaly, otherwise US - 212 MBq
(− 39%)
348 MBq 90 min No WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans
Nodular lymphoma involvement on both sides of the diaphragm  
2 16 years DLBCLoss  +  276 MBq
(− 24%)
363 MBq 90 min No WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans
Nodular lymphoma involvement on both sides of the diaphragm, extensive involvement of the left pelvic bones with cortical bone destruction and infiltration of adjacent muscles Figure 8i–l
3 6 years DLBCL n.d 64 MBq
(− 49%)
126 MBq 135 min Yes WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans
Nodular lymphoma involvement on both sides of the diaphragm Figures 1, 3
4 7 years DLBCL n.d 91 MBq
(− 39%)
148 MBq 110 min No WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans
Nodular lymphoma involvement on both sides of the diaphragm  
5 10 years DLBCLoss n.d 126 MBq
(− 45%)
229 MBq 180 min No WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans
Long segmental lymphoma involvement of the left femur with cortical bone destruction and infiltration of adjacent muscles  
6 10 years T-cell lymphoma n.d Bilateral renal involvement,
otherwise US -
278 MBq
(+ 0%)
277 MBq 110 min No WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans
Nodular lymphoma involvement on both sides of the diaphragm including Waldeyer’s ring. In addition bilateral kidney and skeletal involvement (right femur) Figures 6, 7
7 14 years Burkitt n.d 162 MBq
(− 45%)
292 MBq 45 min No WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans
Nodular lymphoma involvement above diaphragm including Waldeyer’s ring. Moreover, focal skeletal involvement Figures 4, 7, 8a–h
8 15 years T-cell lymphoma + n.d Bilateral renal involvement,
otherwise US -
67 MBq
(− 67%)
200 MBq 70 min No WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans
Nodular lymphoma involvement above diaphragm including left pleura, extended bilateral and focal skeletal involvement (left femur). Waldeyer’s ring involvement most unlikely Figure 2
9 4 years T-cell lymphoma + + 45 MBq
(− 51%)
92 MBq 70 min No WB PET;
WB MR T2-TIRMcor + trans;
WB DWItrans n.e
Nodular lymphoma involvement above diaphragm and left-sided pleural involvement. Waldyer’s ring involvement most unlikely Figure 5
10 17 years DLBCL n.d 239 MBq
(− 31%)
348 MBq 80 min No WB PET;
WB MR T2-TIRMcor + trans
WB DWItrans n. d
Nodular lymphoma involvement above diaphragm  
  1. BMB, Result of Bone Marrow Biopsy; Cor, coronal; DLBCLoss, Primary Osseous Large B-cell Lymphoma; ENTclin, Result of clinical ENT investigation; 18F-FDGadm, Administered 18F-FDG activity; LP, Result of Lumbar Puncture; min, minutes; n.e., not evaluable; TC, Thoracentesis; Trans, transversal; USabdomen, Result of abdominal ultrasound; y, years; Δinject/scan, Time interval from tracer injection to scan start; + , positive for lymphoma; −, negative for lymphoma; Burkitt, Burkitt Lymphoma; DLBCL, Diffuse Large B-cell Lymphoma; DWI, Diffusion Weighted Imaging; f, female; 18F-FDGrecom, Recommended 18F-FDG activity; m, male; n.d., not done; Pat, Patient number; T-cell LL, T-cell Lymphoma; T2-TIRM, T2 weighted Turbo-Inversion Recovery Magnitude; WB, wholebody