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Fig. 8 | EJNMMI Research

Fig. 8

From: Whole-body [18F]-FDG-PET/MRI for staging of pediatric non-Hodgkin lymphoma: first results from a single-center evaluation

Fig. 8

a–l Images from the upper and the middle row belong to the same patient, whereas images from the lower row belong to another patient. The upper row (a–d) shows images of a single lesion in the middle of the right iliac bone (blue arrow). The lesion has increased glucose metabolism on [18F]-FDG-PET images (SUVmax 9.80) (a, c), is hyperintense on MR T2-TIRM images (b) and has restricted diffusion on DWI (ADC about 419 × 10–6 mm2/s) (d). The middle row (e–f) shows images including the biopsy sites on both posterior iliac crests (blue arrows): Both biopsy sites have moderate and diffuse radiotracer uptake on [18F]-FDG-PET images (SUVmax right: 2.65; SUVmax left: 2.74) (e,g), are moderately hyperintense on MR T2-TIRM images (f) and do not show restriction in diffusion on DWI (ADC right: about 1240 × 10–6 mm2/s; ADC left: about 1148 × 10–6 mm2/s) (h). The third row shows extensive lymphoma involvement of the left iliac bone and the biopsy channel (i-l): Lymphoma manifestation from the left iliac bone have markedly increased glucose metabolism on [18F]-FDG-PET images (blue arrows) (i, k), are hyperintense on MR T2-TIRM images (j) and markedly restricted in diffusion on DWI (l). The biopsy channel (red arrows) can be distinguished from the lymphoma lesions by lack of radiotracer uptake (i, k). It is hypointense on MR T2-TIRM images (j) and shows no diffusion restriction on DWI (l)

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