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EJNMMI Research
Fig. 9 | EJNMMI Research

Fig. 9

From: [99mTc]Tc-Galacto-RGD2 integrin αvβ3-targeted imaging as a surrogate for molecular phenotyping in lung cancer: real-world data

Fig. 9

RGD-avid lesion in a patient with lung adenocarcinoma, consistent with αvβ3 expression which confirmed by IHC, flow cytometry and western blot. a–c [99mTc]Tc-Galacto-RGD2 image. d, e IHC showed higher expression of αvβ3 in the tumour cells and higher density of micro-vessel (CD31). f Flow cytometry showed higher expression of integrin β3 in tumour tissue compared with normal lung tissue. g Western blot showed higher integrin β3 expression in primary tumour tissue compared with normal lung tissue

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