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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: [99mTc]Tc-Galacto-RGD2 integrin αvβ3-targeted imaging as a surrogate for molecular phenotyping in lung cancer: real-world data

Fig. 2

[99mTc]Tc-Galacto-RGD2 imaging showed RGD-avid uptake in the primary tumour, lymphadenopathy, and remote metastases in a patient with suspected multiple myeloma. The final diagnosis was lung adenocarcinoma confirmed by bronchoscopic biopsy. a Primary lesion presented in the lung window. b, c Enhanced CT showed primary tumour and lymphadenopathy in the right hilum. d, e Bone scan showed lytic lesion in the right rib and sclerotic lesions in the pelvis. f, g 99mTc-Galacto-RGD2 image showed avid lesions in the right lung and the right hilum. h, i, j IHC staining. h αvβ3 expression. i CD31 expression in neo-vasculature. j CXCR4 expression in tumour tissue

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