Table 2 Classification performance for Aβ PET positivity on ADNI, KBASE, and Severance hospital datasets

Internal validation (ADNI and KBASE)

All

0.811

(0.803, 0.819)

0.733

(0.726, 0.740)

0.678

(0.664, 0.691)

0.785

(0.771, 0.799)

0.709

(0.701, 0.717)

CU

0.717

(0.705, 0.729)

0.748

(0.737, 0.758)

0.381

(0.352, 0.410)

0.870

(0.857, 0.883)

0.422

(0.398, 0.446)

MCI

0.757

(0.746, 0.768)

0.682

(0.672, 0.692)

0.651

(0.636, 0.666)

0.718

(0.698, 0.738)

0.690

(0.680, 0.701)

AD

0.816

(0.789, 0.843)

0.862

(0.848, 0.875)

0.950

(0.939, 0.960)

0.336

(0.283, 0.390)

0.921

(0.912, 0.929)

External validation (Severance hospital)

All

0.798

(0.789, 0.807)

0.690

(0.681, 0.699)

0.768

(0.748, 0.789)

0.612

(0.586, 0.639)

0.712

(0.703, 0.721)

MCI

0.769

(0.762, 0.776)

0.698

(0.691, 0.705)

0.702

(0.688, 0.715)

0.694

(0.675, 0.714)

0.718

(0.711, 0.725)

Demented participants

0.806

(0.803, 0.809)

0.599

(0.573, 0.624)

0.868

(0.850, 0.886)

0.462

(0.414, 0.509)

0.598

(0.587, 0.609)