Table 4 Comparison of different xSPECT quantification as well as blinded reading in patients with suspected prosthetic loosening
xSPECT Quant | xSPECT Bone | xSPECT Quant iMAR | xSPECT Bone iMAR | xSPECT Quant | Blinded reading | Test for superiority* | |
|---|---|---|---|---|---|---|---|
Trainee | Senior | ||||||
Cut-off SUVmax (ROC analysis) | 9.40 | 13.87 | 9.61 | 14.78 | |||
Accuracy | 77.4 (62.4–92.4) | 84.8 (70.6–99.1) | 81.8 (67.5–96.1) | 93.9 (79.6–100) | 81.8 (67.5–96.1) | 84.8 (70.6–99.1) | P = 0.02 |
Sensitivity | 90.0 (63.6–100) | 90.0 (64.0–100) | 90.0 (64.0–100) | 80.0 (54.0–100) | 60.0 (34.0–86.0) | 70.0 (44.0–96.0) | P = 1.0 |
Specificity | 71.4 (53.2–89.6) | 82.6 (65.5–99.7) | 78.3 (61.1–95.4) | 100.0 (82.9–100) | 91.3 (74.2–100) | 91.3 (74.2–100) | P = 0.04 |
Positive predictive value | 60.0 (38.4–81.6) | 69.2 (48.0–90.4) | 64.3 (43.1–85.5) | 100.0 (74.0–100) | 75.0 (49.0–100) | 77.8 (51.8–100) | P = 0.02 |
Negative predictive value | 93.8 (72.2–100) | 95.0 (77.9–100) | 94.7 (77.6–100) | 92.0 (74.9–100) | 84.0 (66.9–100) | 87.5 (70.4–100) | P = 1.0 |