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Fig. 2 | EJNMMI Research

Fig. 2

From: Necrosis binding of Ac-Lys0(IRDye800CW)-Tyr3-octreotate: a consequence from cyanine-labeling of small molecules

Fig. 2

NIR-fluorescence imaging of alive or dead U2OS cells with and without SSTR2-expression, exposed to 800CW-TATE (10 nM in culturing medium). Blocking is performed by co-incubation with DOTA-TATE (10 µM). Fluorescent signal quantified ± SD, n = 12. SSTR2 +  = U2OS cells transfected with SSTR2; SSTR2- = wild-type U2OS cells without SSTR2-expression; 800CW-TATE = Ac-Lys0(IRDye800CW)-Tyr3-octreotate; DOTA-TATE = DOTA0-Tyr3-octreotate

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