Head to head comparison of [99mTc]Tc(CO)3(NTA) and [99mTc]Tc-MAG3 in patients with suspected obstruction

EJNMMI Research

Table 3 Time to peak (min), 20 min/maximum and postvoid/maximum count ratios for the right and left kidneys following administration of NTA and MAG3

Subject	Left kidney TTP (min)		Right kidney TTP (min)		Left kidney 20 min/max		Right kidney 20 min/max		Left kidney PV/max		Right kidney PV/max
Subject	NTA	MAG3	NTA	MAG3	NTA	MAG3	NTA	MAG3	NTA	MAG3	NTA	MAG3
1	2.6	2.8	2.8	3.9	0.12	0.17	0.23	0.56	0.05	0.14	0.1	0.4
2	ID	ID	ID	ID	ID	ID	ID	ID	ID	ID	ID	ID
3	2.5	2.8	2.5	2.5	0.14	0.21	0.08	0.19	0.05	0.12	0.03	0.12
4	AK	AK	ID	ID	AK	AK	ID	ID	AK	AK	ID	ID
5	3.7	3.7	3.2	2.5	0.51	0.82	0.18	0.2	0.79	0.76	0.11	0.11
6	3.2	4	2.1	2.7	0.18	0.23	0.22	0.24	0.09	0.17	0.11	0.16
7	2	2.5	2.6	16	0.08	0.17	0.36	0.97	0.07	0.14	0.11	0.59
8	AK	AK	3.9	10.8	AK	AK	0.58	0.88	AK	AK	0.53	0.65
9	2.4	2.8	2.3	4.8	OT	OT	OT	OT	0.1	0.21	0.16	0.27
10	2.1	2.3	3.2	2.1	OT	OT	OT	OT	0.09	0.2	0.12	0.21
11	2.2	3.1	2.6	3	OT	OT	OT	OT	0.15	0.16	0.08	0.14
13	2.2	7.8	2.4	2.6	0.34	0.79	0.09	0.16	NA	NA	NA	NA
14	3.2	3.5	23.5	21.3	OT	OT	OT	OT	0.13	0.21	1.04	1.08
15	3	3.3	2.1	2.6	0.39	0.64	0.28	0.41	0.65	0.42	0.24	0.28
16	3.2	4.8	2.5	3.8	0.2	0.15	0.09	0.16	0.07	0.09	0.06	0.08
17	2.5	3.8	3.5	6.8	0.6	0.67	0.66	0.83	0.66	0.6	0.45	0.49
18	2.7	3.3	2.1	5.3	0.29	0.46	0.4	0.73	0.24	0.37	0.49	0.69
19	1.9	2.5	2.6	2.7	0.2	0.15	0.14	0.25	0.07	0.09	0.1	0.13
Mean	2.63	3.53	3.99	5.84	0.28	0.41	0.28	0.47	0.23	0.26	0.25	0.36
SD	0.53	1.35	5.23	5.55	0.17	0.28	0.19	0.31	0.26	0.20	0.27	0.29
P	0.0224		0.0677		0.0201		0.0031		0.2334		0.0046

Patient 12 withdrew from the study prior to tracer injection
AK, absent kidney; ID, infiltrated dose; NA, the postvoid image was not acquired and the ratio could not be calculated; OT, patient had to void before the study was completed