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Table 4 Outcomes of the false positive (n = 2) and false negative (n = 1) 11C-choline PET/CT in n = 2 patients

From: A retrospective analysis of the diagnostic performance of 11C-choline PET/CT for detection of hyperfunctioning parathyroid glands after prior negative or discordant imaging in primary hyperparathyroidism

Clinical diagnosis pHPT MEN-IIA
cUS RL, LL RL
99mTc-MIBI-SPECT(/CT) Ectopic Negative
11C-choline PET/CT RL, RU, LU RL
Surgical technique Minimal invasive Minimal invasive
Intra-operative localization RL RU
ioPTH  > 50% decrease NA
Pathology Adenoma, lymph node, thyroiditis Hyperplasia
Follow-up Cured Cured
11C-choline PET/CT result TP, FP, one lesion not confirmed FP, FN
  1. cUS = cervical ultrasonography; pHPT = primary hyperparathyroidism; ioPTH = intraoperative PTH; RL = right lower quadrant; LL = left lower quadrant; RU = right upper quadrant; LU = left upper quadrant; TP = true positive; FP = false positive; MEN = Multiple Endocrine Neoplasia; NA = not available; FN = false negative