EJNMMI Research

Table 2 Summary of aTRV and ICC values for V_T estimates by 2TCM-c and Logan

From: The pharmacokinetics of [¹⁸F]UCB-H revisited in the healthy non-human primate brain

Brain region	2TCM-c V_T (mL/cm³)		Logan (t* = 60) V_T (mL/cm³)
Brain region	aTRV	ICC	aTRV	ICC
Striatum	12%	0,52	11%	0.67
Thalamus	18%	0,05	12%	0.61
Cerebellum	NA	NA	14%	0.32
White matter	24%	0.43	13%	0.62
Frontal cortex	11%	0.84	11%	0.89
Temporal cortex	25%	NA	13%	0.61
Parietal cortex	19%	0.38	12%	0.75

aTRV and ICC calculation of the most relevant V_T estimates obtained with 2TCM-c and Logan. Only estimates at <25%SE were included. For 2TCM, only NHP2 had acceptable estimates in both test-, and retest conditions.

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