Skip to main content

Table 2 Summary of aTRV and ICC values for VT estimates by 2TCM-c and Logan

From: The pharmacokinetics of [18F]UCB-H revisited in the healthy non-human primate brain

Brain region 2TCM-c VT (mL/cm3) Logan (t* = 60) VT (mL/cm3)
aTRV ICC aTRV ICC
Striatum 12% 0,52 11% 0.67
Thalamus 18% 0,05 12% 0.61
Cerebellum NA NA 14% 0.32
White matter 24% 0.43 13% 0.62
Frontal cortex 11% 0.84 11% 0.89
Temporal cortex 25% NA 13% 0.61
Parietal cortex 19% 0.38 12% 0.75
  1. aTRV and ICC calculation of the most relevant VT estimates obtained with 2TCM-c and Logan. Only estimates at <25%SE were included. For 2TCM, only NHP2 had acceptable estimates in both test-, and retest conditions.